Dynamic association between interpersonal functioning and positive symptom dimensions of psychosis over time: A longitudinal study of healthy adolescents

D Collip; JTW Wigman; A Lin; B Nelson; M Oorschot; WAM Vollebergh; J Ryan; G Baksheev; M Wichers; J Van Os; I Myin-Germeys; AR Yung

Journal article

Dynamic association between interpersonal functioning and positive symptom dimensions of psychosis over time: A longitudinal study of healthy adolescents

D Collip, JTW Wigman, A Lin, B Nelson, M Oorschot, WAM Vollebergh, J Ryan, G Baksheev, M Wichers, J Van Os, I Myin-Germeys, AR Yung

Schizophrenia Bulletin | OXFORD UNIV PRESS | Published : 2013

DOI: 10.1093/schbul/sbr115

Abstract

Background: Cross-sectional studies have indicated that alterations in social functioning, particularly interpersonal functioning, are associated with the occurrence of psychotic symptoms and experiences at different levels of the extended psychosis phenotype (ranging from population psychometric expression of liability to overt psychotic disorder). However, more research is needed on the development of this association over time. Methods: Cross-lagged path modeling was used to analyze bidirectional, longitudinal associations between 4 dimensions of subclinical psychotic experiences (persecutory ideation, bizarre experiences, perceptual abnormalities, and magical thinking) and interpersonal ..

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University of Melbourne Researchers

Barnaby Nelson Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

Dutch "Stichting Koningsheide" to J.T.W.W.; National Health and Medical Research Council program grant (566529) to A.L.; National Health and Medical Research Council Senior Research Fellowship and a National Health and Medical Research Council program grant (566529) to A.Y.; NARSAD (the Brain & Behavior Research Foundation) Young Investigator Award and a Ronald Phillip Griffith Fellowship to B.N.; Colonial Foundation; 2006 NARSAD Young Investigator award and by the Dutch Medical Council (VENI and VIDI grant) to I.M.-G.We would like to thank all participants and staff involved in the study. The funding sources had no further role in study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. D.C. and J.T.W.W. contributed equally. Dr J.v.O. is/has been an unrestricted research grant holder with or has received financial compensation as an independent symposium speaker from Eli Lilly, BMS, Lundbeck, Organon, Janssen-Cilag, GSK, AstraZeneca, Pfizer, and Servier, companies which have an interest in the treatment of psychosis. I.M.-G. has received financial compensation as an independent symposium speaker from Eli Lilly, BMS, and Janssen-Cilag. All other authors have no conflict of interests.